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Article

Direct measurement of lymphocyte receptor diversity.

Nucleic acids research - 15 Nov 2003

Ogle Brenda M, Cascalho Marilia, Joao Cristina, Taylor William, West Lori J, Platt Jeffrey L

Abstract excerpt

The ability to mount an immune defense against infectious microorganisms and their products, and against tumors is believed to be a direct function of lymphocyte diversity. Because the diversity of lymphocyte receptor genes is >1000-fold more diverse than the entire genome and varies between genetically identical individuals, measuring lymphocyte diversity has been a daunting challenge. We developed a novel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14602932
DOI: 10.1093/nar/gng139
PMCID: PMC275576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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