Article

Mathematical Characterization of Private and Public Immune Repertoire Sequences

2022-05-17

Abstract excerpt

Diverse T and B cell repertoires play an important role in mounting effective immune responses against a wide range of pathogens and malignant cells. The number of unique T and B cell clones is characterized by T and B cell receptors (TCRs and BCRs), respectively. Although receptor sequences are generated probabilistically by recombination processes, clinical studies found a high degree of sharing of TCRs and BCRs...

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Literature Corpus work: 417f1c9c-279e-56c8-a675-4126f29679c6
DOI: 10.1101/2022.05.17.492232

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