Article

Deep learning-based non-invasive profiling of tumor transcriptomes from cell-free DNA for precision oncology

2026-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Circulating tumor DNA (ctDNA) profiling from liquid biopsies is increasingly adopted as a minimally invasive solution for clinical cancer diagnostic applications. Current methods for inferring gene expression from ctDNA require specialized assays or ultra-deep, targeted sequencing, which preclude transcriptome-wide profiling at single-gene resolution. Herein we jointly introduce Triton, a tool f...

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Literature Corpus work: bfbf18f7-c1db-54cb-91ba-31b9df61e650
DOI: 10.64898/2026.02.10.705188

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