Article

cfDNAanalyzer: a comprehensive toolkit for analyzing cell-free DNA genomic sequencing data in liquid biopsy

2025-06-13

Abstract excerpt

Liquid biopsy, through the analysis of plasma cell-free DNA (cfDNA), is transforming diagnostic medicine by enabling non-invasive insights into the genomic and epigenomic landscape of diseases—most notably cancer. As cfDNA reflects dynamic contributions from multiple tissues, it holds immense potential for early detection, disease monitoring, and personalized treatment. However, the rapid expansion of cfDNA applic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 29a78748-f69c-5351-87d9-886680cc42e6
DOI: 10.1101/2025.06.09.658767

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

cfDNAanalyzer: a comprehensive toolkit for analyzing cell-free DNA genomic sequencing data in liquid biopsyDOI 10.1101/2025.06.09.658767Read

cfDNA UniFlow: A unified preprocessing pipeline for cell-free DNA data from liquid biopsiesSemantic proximity Read

Liquid biopsies across the cancer care continuum.Semantic proximity Read

Integrative modeling of tumor genomes and epigenomes for enhanced cancer diagnosis by cell-free DNA.Semantic proximity Read

Cell‐free DNA‐associated multi‐feature applications in cancer diagnosis and treatmentSemantic proximity Read

Ultra-low coverage fragmentomic model of cell-free DNA for cancer detection based on whole-exome regionsSemantic proximity Read

Multi-modal cell-free DNA genomic and fragmentomic patterns enhance cancer survival and recurrence analysisSemantic proximity Read

Computational Modeling for Circulating Cell-Free DNA in Clinical Oncology.Semantic proximity Read

fRagmentomics: an R package for integrating cell-free DNA fragment features with mutational status to support liquid biopsy interpretation.Semantic proximity Read

Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learningSemantic proximity Read

FinaleToolkit: Accelerating Cell-Free DNA Fragmentation Analysis with a High-Speed Computational ToolkitSemantic proximity Read

Exploring the Role of Circulating Cell-Free DNA in Disease Diagnosis and TherapySemantic proximity Read

Bioinformatics Analysis for Circulating Cell-Free DNA in CancerSemantic proximity Read