Article

Senescent and reactive astrocytes display distinct expression profiles and divergent functional capacities.

2026-06-10

Abstract excerpt

Astrocytes assume multiple phenotypes in the brain in response to stress, injury, inflammation, and aging. Given the complexity of this critical cell type in the CNS, it is important to gain a greater understanding of the differences between these phenotypes and to potentially identify therapeutic approaches to modifying astrocyte function in the context of disease and aging. We compared senescent and reactive ast...

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Literature Corpus work: bfaf6418-43ba-537b-9eb7-e1ca0821e8e5
DOI: 10.64898/2026.06.05.729920

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