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Article

Reactive and Senescent Astroglial Phenotypes as Hallmarks of Brain Pathologies.

International journal of molecular sciences - 30 Apr 2022

Lazic Andrijana, Balint Vanda, Stanisavljevic Ninkovic Danijela, Peric Mina, Stevanovic Milena

Abstract excerpt

Astrocytes, as the most abundant glial cells in the central nervous system, are tightly integrated into neural networks and participate in numerous aspects of brain physiology and pathology. They are the main homeostatic cells in the central nervous system, and the loss of astrocyte physiological functions and/or gain of pro-inflammatory functions, due to their reactivation or cellular senescence, can have...

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PMID: 35563385
DOI: 10.3390/ijms23094995
PMCID: PMC9100382

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