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Article

Astrocyte senescence: Evidence and significance

27 Feb 2019

Abstract excerpt

Astrocytes participate in numerous aspects of central nervous system (CNS) physiology ranging from ion balance to metabolism, and disruption of their physiological roles can therefore be a contributor to CNS dysfunction and pathology. Cellular senescence, one of the mechanisms of aging, has been proposed as a central component of the age dependency of neurodegenerative disorders. Cumulative evidence supports an...

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PMID: 30815970
DOI: 10.1111/acel.12937

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