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Article

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype.

The European journal of neuroscience - 1 Jul 2011

Salminen Antero, Ojala Johanna, Kaarniranta Kai, Haapasalo Annakaisa, Hiltunen Mikko, Soininen Hilkka

Abstract excerpt

Cellular stress increases progressively with aging in mammalian tissues. Chronic stress triggers several signaling cascades that can induce a condition called cellular senescence. Recent studies have demonstrated that senescent cells express a senescence-associated secretory phenotype (SASP). Emerging evidence indicates that the number of cells expressing biomarkers of cellular senescence increases in tissues...

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Identifiers

PMID: 21649759
DOI: 10.1111/j.1460-9568.2011.07738.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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