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Article

Unique signatures of stress-induced senescent human astrocytes

17 Sept 2020

Abstract excerpt

Senescence was recently linked to neurodegeneration and astrocytes are one of the major cell types to turn senescent under neurodegenerative conditions. Senescent astrocytes were detected in Parkinson's disease (PD) patients' brains besides reactive astrocytes, yet the difference between senescent and reactive astrocytes is unclear. We aimed to characterize senescent astrocytes in comparison to reactive...

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PMID: 32949572
DOI: 10.1016/j.expneurol.2020.113466

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