Article
Neurodegenerative Diseases: Unraveling the Heterogeneity of Astrocytes.
Cells - 27 May 2024
Santiago-Balmaseda Alberto, Aguirre-Orozco Annai, Valenzuela-Arzeta Irais E, Villegas-Rojas Marcos M, Pérez-Segura Isaac, Jiménez-Barrios Natalie, Hurtado-Robles Ernesto, Rodríguez-Hernández Luis Daniel, Rivera-German Erick R, Guerra-Crespo Magdalena, Martinez-Fong Daniel, Ledesma-Alonso Carlos, Diaz-Cintra Sofía, Soto-Rojas Luis O
Abstract excerpt
The astrocyte population, around 50% of human brain cells, plays a crucial role in maintaining the overall health and functionality of the central nervous system (CNS). Astrocytes are vital in orchestrating neuronal development by releasing synaptogenic molecules and eliminating excessive synapses. They also modulate neuronal excitability and contribute to CNS homeostasis, promoting neuronal survival by clearance...
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