Article

NuMA interaction with chromatin is vital for proper nuclear architecture in human cells

2020-05-03

Abstract excerpt

NuMA is an abundant long-coiled-coil protein that plays a prominent role in spindle organization during mitosis. In interphase, NuMA is localized to the nucleus and hypothesized to control gene expression and chromatin organization. However, because of the prominent mitotic phenotype upon NuMA loss, its precise function in the interphase nucleus remains elusive. Here, we report that NuMA is associated with chromat...

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Literature Corpus work: befc226a-2e8d-5cb1-896a-63d23f7fc342
DOI: 10.1101/2020.05.02.073767

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