m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer.

doi:10.1016/j.ccell.2020.02.004

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer.

Cancer cell - 16 Mar 2020

Huang Huilin, Weng Hengyou, Chen Jianjun

Abstract excerpt

N6-Methyladenosine (m6A) RNA modification has emerged in recent years as a new layer of regulatory mechanism controlling gene expression in eukaryotes. As a reversible epigenetic modification found not only in messenger RNAs but also in non-coding RNAs, m6A affects the fate of the modified RNA molecules and plays important roles in almost all vital bioprocesses, including cancer development. Here we review the...

Topics

Adenosine
Epigenesis, Genetic
Female
Gene Expression Regulation
Gene Expression Regulation, Neoplastic
Humans
Immunotherapy
Male
Mutation
Neoplasms
RNA, Messenger
RNA, Untranslated

Source

Open in PubMed Open full text

Identifiers

PMID: 32183948
DOI: 10.1016/j.ccell.2020.02.004
PMCID: PMC7141420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics