Article

METTL4 catalyzes m6Am methylation in <i>U2 snRNA</i> to regulate pre-mRNA splicing

2020-01-25

Abstract excerpt

N 6 -methylation of 2’-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N 6 ,2’-O-dimethyladenosine (m6Am). Identification of the methyltransferase responsible for m6Am catalysis has accelerated studies on the function of m6Am in RNA processing. While m6Am is generally found in the first transcribed nucleotide of mRNAs, the modification is also found internally within U2 snRNA . However, the...

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Literature Corpus work: 5e11574a-23f4-5e7c-ae8a-e411e6cd361b
DOI: 10.1101/2020.01.24.917575

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