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Human Sperm-Induced Cell-Cell Fusion Requiring JUNO (hSPICER): A paradigm shift to test sperm fertilizing potential

2026-05-11

Abstract excerpt

Current evaluation of male fertility is largely based on indirect sperm parameters such as viability, concentration, morphology, and motility; however, each of these parameters, alone or combined, has been shown to have limited predictive value for successful fertilization. To address this problem, we introduce hSPICER (human SPerm-Induced CEll-cell fusion Requiring JUNO), an assay that evaluates sperm function ba...

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Literature Corpus work
be553e3b-e020-57a7-a42d-01e98c9f591f
DOI
10.64898/2026.05.07.723220
Open publication

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