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Article

Sperm-Egg Fusion: A Molecular Enigma of Mammalian Reproduction

13 Jun 2014

Abstract excerpt

The mechanism of gamete fusion remains largely unknown on a molecular level despite its indisputable significance. Only a few of the molecules required for membrane interaction are known, among them IZUMO1, which is present on sperm, tetraspanin CD9, which is present on the egg, and the newly found oolema protein named Juno. A concept of a large multiprotein complex on both membranes forming fusion machinery has...

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PMID: 24933635
DOI: 10.3390/ijms150610652

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Sperm-Egg Fusion: A Molecular Enigma of Mammalian ReproductionPMID 24933635Read ↗

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