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Article

Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex

14 Jun 2016

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27309818
DOI: 10.1038/nature18595

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complexPMID 27309818Read ↗

Novel insights into the molecular mechanism of sperm–egg fusion via IZUMO1Semantic proximity Read ↗

Juno is the egg Izumo receptor and is essential for mammalian fertilizationSemantic proximity Read ↗

Genetic Diversity in the IZUMO1-JUNO Protein-Receptor Pair Involved in Human ReproductionSemantic proximity Read ↗

Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.Semantic proximity Read ↗

A conserved fertilization complex bridges sperm and egg in vertebratesSemantic proximity Read ↗

Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.Semantic proximity Read ↗

The mechanism of sperm–egg interaction and the involvement of IZUMO1 in fusionSemantic proximity Read ↗

Sperm-Egg Fusion: A Molecular Enigma of Mammalian ReproductionSemantic proximity Read ↗

The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggsSemantic proximity Read ↗

Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm–egg fusion in miceSemantic proximity Read ↗

Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilizationSemantic proximity Read ↗

Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13Semantic proximity Read ↗

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