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A <i>C. elegans</i> genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle function

2020-12-02

Abstract excerpt

At the neuromuscular junction (NMJ), postsynaptic ionotropic acetylcholine receptors (AChRs) transduce a chemical signal released from a cholinergic motor neuron into an electrical signal to induce muscle contraction. To identify regulators of postsynaptic function, we conducted a genome-wide RNAi screen for genes required for proper response to levamisole, a pharmacological agonist of ionotropic L-AChRs at the C...

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Literature Corpus work
be2d4868-5d99-51dd-a546-6fd2ba2990e3
DOI
10.1101/2020.12.01.407213
Open publication

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A <i>C. elegans</i> genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle functionDOI 10.1101/2020.12.01.407213
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