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Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in <i>C. elegans</i>

2020-02-21

Abstract excerpt

Complex I deficiency represents the most frequent pathogenetic cause of human mitochondriopathies. Therapeutic options for these neurodevelopmental life-threating disorders do not exist, partly due to the scarcity of appropriate model systems to study them. Caenorhabditis elegans is a genetically tractable model organism widely used to investigate neuronal pathologies. Here, we generated new C. elegans models fo...

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Literature Corpus work
5bac6290-b465-5911-91d3-c514facf8c21
DOI
10.1101/2020.02.20.957225
Open publication

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Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in <i>C. elegans</i>DOI 10.1101/2020.02.20.957225
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