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Article

A transmembrane protein required for acetylcholine receptor clustering in Caenorhabditis elegans.

Nature - 30 Sept 2004

Gally Christelle, Eimer Stefan, Richmond Janet E, Bessereau Jean-Louis

Abstract excerpt

Clustering neurotransmitter receptors at the synapse is crucial for efficient neurotransmission. Here we identify a Caenorhabditis elegans locus, lev-10, required for postsynaptic aggregation of ionotropic acetylcholine receptors (AChRs). lev-10 mutants were identified on the basis of weak resistance to the anthelminthic drug levamisole, a nematode-specific cholinergic agonist that activates AChRs present at...

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Identifiers

PMID: 15457263
DOI: 10.1038/nature02893
PMCID: PMC3781939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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