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Two populations of heteromeric acetylcholine receptors are present at Caenorhabditis elegans neuromuscular junctions.

Genetics - 4 Apr 2026

Maiellano Greta, Luccardini Camilla, Romatif Océane, Jospin Maëlle, D'Alessandro Manuela, Bessereau Jean-Louis

Abstract excerpt

Ligand-gated acetylcholine receptors (AChRs) are pentameric transmembrane proteins that display extensive molecular diversity through combinatorial assembly of subunits. In the nematode Caenorhabditis elegans, this diversity is exceptionally expanded, with nearly 60 AChR subunit genes, yet the composition and function of many receptor subtypes remain poorly defined. At neuromuscular junctions (NMJs), L-AChRs are...

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PMID: 41642690
DOI: 10.1093/genetics/iyag012

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ACR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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