Article

Evolutionary diversity of the control of the azole response by Tra1 across yeast species

2023-09-06

Abstract excerpt

<h4>ABSTRACT</h4> Tra1 is an essential co-activator protein of the yeast SAGA and NuA4 acetyltransferase complexes that regulate gene expression through multiple mechanisms including the acetylation of histone proteins. Tra1 is a pseudokinase of the PIKK family characterized by a C-terminal PI3K domain with no known kinase activity. However, mutations of specific arginine residues to glutamine in the PI3K domains...

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Literature Corpus work: bdaa752e-17d8-5444-bf9a-a3e4a96c6085
DOI: 10.1101/2023.09.05.556458

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