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The TAC1 Gene in Candida albicans: Structure, Function, and Role in Azole Resistance: A Mini-Review.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jul 2024

Mahdizade Amir Hossein, Hoseinnejad Akbar, Ghazanfari Mona, Boozhmehrani Mohammad Javad, Bahreiny Seyed Sobhan, Abastabar Mahdi, Galbo Roberta, Giuffrè Letterio, Haghani Iman, Romeo Orazio

Abstract excerpt

Candidiasis is a common fungal infection caused by Candida species, with Candida albicans being the most prevalent. Resistance to azole drugs, commonly used to treat Candida infections, poses a significant challenge. Transcriptional activator candidate 1 (TAC1) gene has emerged as a key player in regulating drug resistance in C. albicans. This review explores the structure and function of the TAC1 gene and its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38770776
DOI: 10.1089/mdr.2023.0334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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