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Fpk1 regulates Cdr1 expression and ergosterol homeostasis in <i>Nakaseomyces glabratus</i> ( <i>Candida glabrata</i> ) during azole exposure.

2026-08-14

Abstract excerpt

Azoles remain the most common antifungal therapy worldwide. However, Nakaseomyces glabratus (previously named Candida glabrata ) has a high intrinsic tolerance against azole drugs. The organism can also accrue additional chromosomal mutations to elevate its resistant level during treatment. These genetic alterations often result in overexpression of the ABC transmembrane transporter Cdr1, which has been shown to...

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Literature Corpus work
1c4ca686-5927-54a6-a6ed-aefeb1587557
DOI
10.64898/2026.08.14.744811
Open publication

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Fpk1 regulates Cdr1 expression and ergosterol homeostasis in <i>Nakaseomyces glabratus</i> ( <i>Candida glabrata</i> ) during azole exposure.DOI 10.64898/2026.08.14.744811
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