Article
Histone Acetylation Regulator Gcn5 Mediates Drug Resistance and Virulence of Candida glabrata
6 Jun 2022
Abstract excerpt
As an important and successful human pathogen, Candida glabrata is known for its swift adaptation and rapid acquisition of resistance to the most commonly used antifungal agents, resulting in therapeutic failure in clinical settings. Here, we describe that the histone acetyltransferase Gcn5 is a key factor in adapting to antifungal pressure and developing resistance in C. glabrata. The results provide new...