Article

Bone response to intermittent parathyroid hormone (PTH) is both genetic and sex specific

2026-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Teriparatide (PTH 1-34) is an anabolic agent used to treat osteoporosis, yet clinical response varies widely among patients. To investigate genetic and sex-specific determinants of skeletal response, we administered intermittent PTH to male and female mice from eight genetically diverse inbred strains. Mice were treated for four weeks, and bone phenotypes were assessed via DXA, microCT, and mech...

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Literature Corpus work: bd55a8f0-061b-560c-a6a0-5af456e63d4d
DOI: 10.64898/2026.06.09.729629

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