Article

Genome-wide association study in Collaborative Cross mice reveals a role for <i>Rhbdf2</i> in skeletal homeostasis

2016-12-16

Abstract excerpt

Osteoporosis, the most common bone disease, is characterized by a low bone mass and increased risk of fractures. Importantly, individuals with the same bone mineral density (BMD), as measured on two dimensional (2D) radiographs, have different risks for fracture, suggesting that microstructural architecture is an important determinant of skeletal strength. Here we took advantage of the rich phenotypic and genetic...

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Literature Corpus work: c25f3be1-70de-5e55-9a4c-545cf5b0c27b
DOI: 10.1101/094698

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