Article
Phenotypic characterization of mice bred for high and low peak bone mass.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2001
Klein R F, Shea M, Gunness M E, Pelz G B, Belknap J K, Orwoll E S
Abstract excerpt
In humans, peak bone mineral density (BMD) is a highly heritable trait and a strong determinant of subsequent osteoporotic fracture risk. To identify the genetic factors responsible for variation in peak BMD, investigators have turned to animal models. In this study we examined the heritability o...
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