Article
Genetic variation in bone-regenerative capacity among inbred strains of mice.
Bone - 1 Aug 2001
Li X, Gu W, Masinde G, Hamilton-Ulland M, Rundle C H, Mohan S, Baylink D J
Abstract excerpt
Genetic variation in bone-regenerative capacity has not been studied in any animal model system. We developed a "drill-hole" model in the tail vertebra of inbred strains of mice that allows us to reproducibly introduce an injury with a defined boundary and quantify the rate of bone healing using the combination of high-resolution Faxitron X-ray imaging and the ChemiImager 4000 Low Light Imaging System. Using this...
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