Article

Genetic Variability affects the Skeletal Response to Unloading

2020-06-28

Abstract excerpt

Mechanical unloading decreases bone volume and strength. In humans and mice, bone mineral density is highly heritable, and in mice the response to changes in loading varies with genetic background. Thus, genetic variability may affect the response of bone to unloading. As a first step to identify genes involved in bone response to unloading, we evaluated the effects of unloading in eight inbred mouse strains: C57B...

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Literature Corpus work: 4fca88e4-1881-52ee-ae23-637dadbc3eca
DOI: 10.1101/2020.06.26.174326

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