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The antimicrobial metabolite nisin Z reduces intestinal tumorigenesis and modulates the cecal microbiome in Apc <sup>Min/+</sup> mice

2025-05-19

Abstract excerpt

Nisin Z, an antimicrobial metabolite produced by Lactococcus lactis spp., has been safely used as a food preservative for many years. Nisin Z also showed promising activity against various cancer types in vitro , and significantly reduced tumor size in an ectopic head and neck cancer model. Here, we investigate the activity of nisin Z for colorectal cancer treatment and observed an in vitro reduction in cellula...

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Identifiers and source

Literature Corpus work
bd1787e2-4237-51fa-954e-4e272c614279
DOI
10.1101/2025.05.18.654755
Open publication

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The antimicrobial metabolite nisin Z reduces intestinal tumorigenesis and modulates the cecal microbiome in Apc <sup>Min/+</sup> miceDOI 10.1101/2025.05.18.654755
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