Article
Tigecycline reduces tumorigenesis in colorectal cancer via inhibition of cell proliferation and modulation of immune response.
2023-02-02
Abstract excerpt
<h4>Background: </h4> and Purpose: Colorectal cancer (CRC) is one of the cancers with the highest incidence in which APC gene mutations occurs in almost 80% of patients. This mutation leads to β-catenin aberrant accumulation and an uncontrolled proliferation. Apoptosis evasion, changes in the immune response and microbiota composition are also events that arise in CRC. Tetracyclines are drugs with proven antibioti...
Topics
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- Cancer-related Molecular Pathways
- Cancer Research and Treatments
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Pancreatic and Hepatic Oncology Research
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- b2f9b6ef-5ca4-50ab-b0b3-9815ac6afee1
- DOI
- 10.22541/au.167535386.67797512/v1
