Article
Induction of inflammatory bowel disease accelerates adenoma formation in Min +/- mice.
Surgery - 1 Jun 2006
Huang Emina H, Park Juliet C, Appelman Henry, Weinberg Alan D, Banerjee Mousumi, Logsdon Craig D, Schmidt Ann Marie
Abstract excerpt
BACKGROUND: The accelerated incidence of colorectal carcinoma in individuals with inflammatory bowel disease suggests that cellular perturbation triggered by chronic inflammation is linked to the development of dysplasia and neoplastic transformation. To test the mechanistic links between these processes, we employed the following murine strains: (1) multiple intestinal neoplasia (Min) +/- mice, bearing a...
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