Article

Colorectal cancer detection and treatment with engineered probiotics

2023-04-05

Abstract excerpt

Bioengineered probiotics enable new opportunities to improve colorectal cancer (CRC) screening, prevention and treatment strategies. Here, we demonstrate the phenomenon of selective, long-term colonization of colorectal adenomas after oral delivery of probiotic E. coli Nissle 1917 (EcN) to a genetically-engineered murine model of CRC predisposition. We show that, after oral administration, adenomas can be monitor...

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Literature Corpus work: 7d8d6ab5-391c-54ca-9866-f3821169de87
DOI: 10.1101/2023.04.03.535370

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