Article

Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype Study

2025-04-29

Abstract excerpt

<h4>Background</h4> Studies of germline variants in prostate cancer (PCa) have largely focused on their connections to cancer predisposition. However, an understanding of how heritable factors contribute to cancer progression and metastasis remain limited. <h4>Objective</h4> To identify low frequency to rare germline nonsynonymous variants associated with increased risk for metastatic PCa (mPCa), while providing f...

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Literature Corpus work: bd0566a5-7e0d-5974-bb53-1c11ea4ba0b4
DOI: 10.1101/2025.04.28.25326584

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