Article
Whole exome germline sequencing in early-onset prostate cancer patients: Genomic findings and clinical outcomes.
The Prostate - 1 Jan 2024
Siegelmann-Danieli Nava, Neiman Victoria, Bareket-Samish Avital, Berger Racheli, Peretz Asaf, Alapi Hillel, Tsur Erez, Patalon Tal, Beller Daniella, Rimler Galit, Chodick Gabriel, Shohat Mordechai
Abstract excerpt
BACKGROUND: Whole exome sequencing (WES) furthered our understanding of various tumors. We assessed the occurrence of germline likely pathogenic/pathogenic (LP/P) variants, disease features, and clinical outcomes in early-onset prostate cancer. METHODS: This retrospective study (N = 134) included consecutive prostate cancer patients who donated blood samples for research purposes to the Kahn-Sagol-Maccabi...
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