Article

Pathogenic germline variants in a racially diverse real-world cohort of prostate cancer patients

2025-08-15

Abstract excerpt

<h4>Importance</h4> Pathogenic germline variant (PGV) rates in cancer risk genes and their association with clinical pathological features inform genetic testing practices for prostate cancer (PCa) patients. <h4>Objective</h4> To determine the rate of PCa risk gene PGVs in a real-world, diverse cohort of PCa patients and identify clinical predictors of carrier status. <h4>Design, Setting, Participants, Main Outc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 21e0815b-0b7b-50b2-9a73-c142518cc4c9
DOI: 10.1101/2025.08.13.25333614

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pathogenic germline variants in a racially diverse real-world cohort of prostate cancer patientsDOI 10.1101/2025.08.13.25333614Read

Pathogenic Germline Variants in a Racially Diverse Real-World Cohort of Patients With Prostate Cancer.Semantic proximity Read

Identifying and Characterizing the Germinal Genetic Landscape of Men with Prostate Cancer—A Real‐Life Retrospective Multi‐Centered StudySemantic proximity Read

Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testingSemantic proximity Read

Prevalence of Germline Variants in Prostate Cancer and Implications for Current Genetic Testing GuidelinesSemantic proximity Read

Patterns and Frequency of Pathogenic Germline Variants Among Prostate Cancer Patients Utilizing Multi-Gene Panel Genetic TestingSemantic proximity Read

Clinical Germline Testing Results of Men With Prostate Cancer: Patient-Level Factors and Implications of NCCN Guideline Expansion.Semantic proximity Read

Germline Variant Spectrum Among African American Men Undergoing Prostate Cancer Germline Testing: Need for Equity in Genetic TestingSemantic proximity Read

Detection of Germline Variants in Patients With Localized and Metastatic Prostate Cancer Through Guideline-Based Testing.Semantic proximity Read

Gene-based Confirmatory Germline Testing Following Tumor-only Sequencing of Prostate Cancer.Semantic proximity Read

Recent Insights on Genetic Testing in Primary Prostate Cancer.Semantic proximity Read

Germline Pathogenic Variants in 7636 Japanese Patients With Prostate Cancer and 12 366 ControlsSemantic proximity Read

Inherited Mutations in Men Undergoing Multigene Panel Testing for Prostate Cancer: Emerging Implications for Personalized Prostate Cancer Genetic EvaluationSemantic proximity Read