Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline variants in early and late-onset Brazilian prostate cancer patients.

Urologic oncology - 1 Mar 2024

Coelho Karoline Brito Caetano Andrade, Squire Jeremy A, Duarte Kelly Gomes, Sares Cláudia Tarcila Gomes, Moreda Natalia Alonso, Pereira Jonatas Luiz, da Silva Israel Tojal, Defelicibus Alexandre, Aoki Mateus Nóbrega, Rivas Javier De Las, Dos Reis Rodolfo Borges, Zanette Dalila Lucíola

Abstract excerpt

BACKGROUND: The median age for Prostate Cancer (PCa) diagnosis is 66 years, but 10% are diagnosed before 55 years. Studies on early-onset PCa remain both limited and controversial. This investigation sought to identify and characterize germline variants within Brazilian PCa patients classified as either early or later onset disease. METHODS: Peripheral blood DNA from 71 PCa patients: 18 younger (≤ 55 years) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Germ Cells

Share to Germ-Line Mutation

Share to Mutation

Share to Prostate Cancer Diagnosis and Treatment

Share to Prostatic Neoplasms

Source

Identifiers

PMID: 38311546
DOI: 10.1016/j.urolonc.2024.01.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline variants in early and late-onset Brazilian prostate cancer patients.PMID 38311546Read ↗

Prostate Cancer Germline Variations and Implications for Screening and Treatment.Semantic proximity Read ↗

Genetic Risk Prediction for Prostate Cancer: Implications for Early Detection and Prevention.Semantic proximity Read ↗

Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer.Semantic proximity Read ↗

Identifying and Characterizing the Germinal Genetic Landscape of Men with Prostate Cancer—A Real‐Life Retrospective Multi‐Centered StudySemantic proximity Read ↗

Recent Insights on Genetic Testing in Primary Prostate Cancer.Semantic proximity Read ↗

Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype StudySemantic proximity Read ↗

Whole exome germline sequencing in early-onset prostate cancer patients: Genomic findings and clinical outcomes.Semantic proximity Read ↗

BRCA2 gene mutation and prostate cancer risk. Comprehensive review and update.Semantic proximity Read ↗

Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African menSemantic proximity Read ↗

Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors.Semantic proximity Read ↗

Prevalence and Clinical Associations of Germline DDR Variants in Prostate Cancer: Real-World Evidence from a 122-Patient Turkish Cohort.Semantic proximity Read ↗

Pathogenic germline variants in a racially diverse real-world cohort of prostate cancer patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.