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Metastatic prostate cancer is associated with distinct higher frequency of genetic mutations at diagnosis.

Urologic oncology - 1 Nov 2023

Al-Toubat Mohammed, Serrano Samuel, Elshafei Ahmed, Koul Kashyap, Feibus Allison H, Balaji K C

Abstract excerpt

INTRODUCTION AND OBJECTIVES: We explored characteristic genetic mutations associated with metastatic prostate cancer (PCa) by comparing next generation sequencing (NGS) data between men with or without metastatic disease at diagnosis. METHODS: We queried the American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange (GENIE) registry for men diagnosed with PCa. Patients were...

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PMID: 37838503
DOI: 10.1016/j.urolonc.2023.09.014

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