Article

Genome-wide CRISPR knockout cell screening platform for the disease vector tick species <i>Ixodes scapularis</i>

2026-05-07

Abstract excerpt

The black legged tick, Ixodes scapularis , is a vector of the bacterium that causes Lyme disease and several other illnesses, including anaplasmosis, babesiosis, and tick-borne encephalitis. Although high-quality genome annotations are available for I. scapularis , functional understanding of I. scapularis genes is limited. To address this, we developed a platform for genome-wide CRISPR-Cas9 knockout screening...

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Literature Corpus work: bcf974ed-58f0-5490-8240-3b6e1c53a721
DOI: 10.64898/2026.05.05.721418

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