Article

A CRISPR interference platform for selective downregulation of gene expression in <i>Borrelia burgdorferi</i>

2020-10-12

Abstract excerpt

<h4>ABSTRACT</h4> The spirochete Borrelia burgdorferi causes Lyme disease, an increasingly prevalent infection. While previous studies have provided important insight into B. burgdorferi biology, many aspects, including basic cellular processes, remain underexplored. To help speed up the discovery process, we adapted a CRISPR interference (CRISPRi) platform for use in B. burgdorferi . For efficiency and flexib...

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Literature Corpus work: 58711632-50d2-5e8c-bc93-c28db576ac76
DOI: 10.1101/2020.10.12.335471

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