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Article

A comprehensive genetic catalog of human double-strand break repair

2024-08-03

Abstract excerpt

The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. By employing parallel in-pool profiling of Cas9-induced indels within a genome-wide knockout library, we present a comprehensive catalog detailing how virtually every human gene influences the DSB repair process. This REPAIRome resource is validated through the identification of novel mechanisms, pat...

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Identifiers and source

Literature Corpus work
38f5fde2-7e93-5caa-bdd2-f640f36a2588
DOI
10.1101/2024.08.03.606369
Open publication

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A comprehensive genetic catalog of human double-strand break repairDOI 10.1101/2024.08.03.606369
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