Article

Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs

2022-06-01

Abstract excerpt

Expression quantitative trait locus (eQTL) studies illuminate genomic variants that regulate specific genes and contribute to fine-mapped loci discovered via genome-wide association studies (GWAS). Efforts to maximize their accuracy are ongoing. Using 240 glomerular (GLOM) and 311 tubulointerstitial (TUBE) micro-dissected samples from human kidney biopsies, we discovered 5,371 GLOM and 9,787 TUBE eQTLs by incorpor...

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Literature Corpus work: bb7df4b9-615e-59ea-810f-6cd9097f7a05
DOI: 10.1101/2022.06.01.494352

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