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A catalog of genetic loci associated with kidney function from analyses of a million individuals

31 May 2019

Abstract excerpt

Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through trans-ancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these, 147 were likely to be relevant for kidney function on the basis of associations with the...

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PMID: 31152163
DOI: 10.1038/s41588-019-0407-x

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