Back to search

Article

Genetic Pleiotropy Underpinning Adiposity and Inflammation in Self-Identified Hispanic/Latino Populations

2022-06-23

Abstract excerpt

<h4>Background: </h4> Concurrent variation in adiposity and inflammation suggests potential shared functional pathways and pleiotropic disease underpinning. Yet, exploration of pleiotropy in the context of adiposity-inflammation has been scarce, and none has included self-identified Hispanic/Latino populations. Given the high level of ancestral diversity in Hispanic American population, genetic studies may reveal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ba866512-9068-5b70-90c8-2ca6ab67aee4
DOI
10.21203/rs.3.rs-1750741/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic Pleiotropy Underpinning Adiposity and Inflammation in Self-Identified Hispanic/Latino PopulationsDOI 10.21203/rs.3.rs-1750741/v1
Phenome-wide search for pleiotropic loci highlights key genes and molecular pathways for human complex traitsSemantic proximity
Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.Semantic proximity
Pleiotropic genes for metabolic syndrome and inflammation.Semantic proximity
A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans.Semantic proximity
Genetic pleiotropy underlying obesity and autoimmune disorders: a large-scale cross-trait gwas analysis in European ancestry populations.Semantic proximity
Integrated Genomic and Transcriptomic Study Reveals MAPK11 and PER1 as Important Obesity Susceptibility Genes in a High-Risk Hispanic/Latino Population.Semantic proximity
Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.Semantic proximity
Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study.Semantic proximity
A whole genome linkage scan identifies multiple chromosomal regions influencing adiposity-related traits among Samoans.Semantic proximity
Pleiotropy of cardiometabolic syndrome with obesity-related anthropometric traits determined using empirically derived kinships from the Busselton Health Study.Semantic proximity
Examining How Our Shared Evolutionary History Shapes Future Disease Outcomes.Semantic proximity
Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.Semantic proximity
Select a neighboring publication to make it the new centre.