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Article

Examining How Our Shared Evolutionary History Shapes Future Disease Outcomes.

Global heart - 1 Jun 2017

Tekola-Ayele Fasil, Peprah Emmanuel

Abstract excerpt

Cardiometabolic diseases are major contributors to mortality and morbidity, and their burden displays global and regional disparities. Gene-environment interactions contribute to the pathogenesis of cardiometabolic diseases. Population differences in genetic structure, ancient environmental pressures that shape the human genome, and early life environmental adversities (e.g., in utero conditions) all contribute...

Topics

Cardiovascular Diseases
Ethnicity
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Global Health
Humans
Metabolic Diseases
Models, Genetic
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28302556
DOI: 10.1016/j.gheart.2017.01.008
PMCID: PMC5583013

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