Article
A whole genome linkage scan identifies multiple chromosomal regions influencing adiposity-related traits among Samoans.
Annals of human genetics - 1 Nov 2008
Dai F, Sun G, Aberg K, Keighley E D, Indugula S R, Roberts S T, Smelser D, Viali S, Jin L, Deka R, Weeks D E, McGarvey S T
Abstract excerpt
We conducted a genome-wide scan in 46 pedigrees, with 671 phenotyped adults, from the independent nation of Samoa to map quantitative trait loci (QTLs) for adiposity-related phenotypes, including body mass index (BMI), abdominal circumference (ABDCIR), percent body fat (%BFAT), and fasting serum leptin and adiponectin. A set of 378 autosomal and 14 X chromosomal microsatellite markers were genotyped in 572 of the...
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