Article
Pleiotropy of cardiometabolic syndrome with obesity-related anthropometric traits determined using empirically derived kinships from the Busselton Health Study.
Human genetics - 1 Jan 2018
Cadby Gemma, Melton Phillip E, McCarthy Nina S, Almeida Marcio, Williams-Blangero Sarah, Curran Joanne E, VandeBerg John L, Hui Jennie, Beilby John, Musk A W, James Alan L, Hung Joseph, Blangero John, Moses Eric K
Abstract excerpt
Over two billion adults are overweight or obese and therefore at an increased risk of cardiometabolic syndrome (CMS). Obesity-related anthropometric traits genetically correlated with CMS may provide insight into CMS aetiology. The aim of this study was to utilise an empirically derived genetic relatedness matrix to calculate heritabilities and genetic correlations between CMS and anthropometric traits to...
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