Article

Differentiating amyloid beta spread in autosomal dominant and sporadic Alzheimer’s disease

2021-06-28

Abstract excerpt

Amyloid-beta (Aβ) deposition is one of the hallmark pathologies in both sporadic Alzheimer’s disease (sAD) and autosomal dominant Alzheimer’s disease (ADAD), the latter of which is caused by mutations in genes involved in Aβ processing. Despite Aβ deposition being a centerpiece to both sAD and ADAD, some differences between these AD subtypes have been observed with respect to the spatial pattern of Aβ. Previous wo...

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Literature Corpus work: 864e5655-bb17-5f08-a880-5596b5458f3f
DOI: 10.1101/2021.06.25.449939

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