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Dynamic interplay between structural variations and 3D chromosome organization in pancreatic cancer

2021-12-16

Abstract excerpt

<h4>Summary</h4> Structural variations (SVs) are the greatest source of variation in the genome and can lead to oncogenesis. However, the identification and interpretation of SVs in human pancreatic cancer remain largely undefined due to technological limitations. Here, we investigate the spectrum of SVs and three-dimensional (3D) chromatin architecture in human pancreatic ductal epithelial cell carcinogenesis by...

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Literature Corpus work
63be12dd-7f01-5220-825c-02ebca80705b
DOI
10.1101/2021.12.15.471847
Open publication

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Dynamic interplay between structural variations and 3D chromosome organization in pancreatic cancerDOI 10.1101/2021.12.15.471847
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