Article

Template-based genome editing directed by the SviCas3

2023-03-01

Abstract excerpt

RNA-guided genome editing based on the CRISPR-Cas system is currently the most effective genome editing technique. Here, we report that SviCas3 from the subtype I-B-Svi Cas system in Streptomyces virginiae IBL14 is an RNA-guided and DNA-guided DNA endonuclease suitable for the gene and/or base editing of prokaryotic and eukaryotic cell genomes. The genome editing efficiency of SviCas3 guided by DNA was no less tha...

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Literature Corpus work: b9d76a40-d85f-518a-ab88-49e039ade464
DOI: 10.21203/rs.3.rs-2518711/v1

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